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Mark A Espeland , PhD, FASA
Department Chair

Espeland, Mark A
DBS Administration
Department of Biostatistical Sciences
Division of Public Health Sciences
Wake Forest University Health Sciences

Admin Assistant/Secretary: Terri Windham
One Technology Place (OTP)
Room Number: 204
Medical Center Blvd.
Winston-Salem, North Carolina 27157-1063

Telephone: 336-716-2826
Email: mespelan@wfubmc.edu

EDUCATION:
BA (Mathematics), Arizona State University, 1974
MA (Statistics), University of Rochester, 1976
PhD (Statistics), University of Rochester, 1981 

RESEARCH:
Dr. Espeland's primary research interest has been the analysis of data from clinical trials and epidemiologic cohort studies. This has led him to examine research questions in diverse fields such as women's health, aging, diabetes, cardiovascular disease, sickle cell disease, cognition, and obesity. His methodological interests are in developing models from incomplete data and error-prone data. As applications of this methodology, he has explored relationships involving ultrasonographic measurements, diet intake measures, and measures of maturation and growth and has authored/coauthored more than 170 biomedical journal articles.

Dr. Espeland has been involved in leadership roles of coordinating and administrative centers for many major multi-center studies including the Action for Health in Diabetes (Look AHEAD), the Trial of Nonpharmacologic Interventions in the Elderly (TONE), the Women's Health Initiative Memory Study (WHIMS), the Type 1 Diabetes Genetics Consortium, the Postmenopausal Estrogen/Progestins Intervention (PEPI) clinical trial, the Asymptomatic Carotid Artery Progression Study (ACAPS), and the Cooperative Study of Sickle Cell Disease (CSSCD).

Dr. Espeland is a frequent consultant to the National Insitutes of Health and has served on over two dozen Data and Safety Monitoring Boards / Advisory Panels for major studies. He has been an elected member on the Board of Directors for the Society for Clinical Trial.
 

PUBLICATIONS (10 most recent):
View all publications for this profile>>

Ding J;Hsu FC;Harris TB;Liu Y;Kritchevsky SB;Szklo M;Ouyang P;Espeland MA;Lohman KK;Criqui MH;Allison M;Bluemke DA;Carr JJ;  The association of pericardial fat with incident coronary heart disease: the Multi-Ethnic Study of Atherosclerosis (MESA); Am J Clin Nutr ; 2009 Sep; 90:499-504
Williamson JD;Espeland M;Kritchevsky SB;Newman AB;King AC;Pahor M;Guralnik JM;Pruitt LA;Miller ME;  Changes in cognitive function in a randomized trial of physical activity: results of the lifestyle interventions and independence for elders pilot study; J Gerontol A Biol Sci Med Sci ; 2009 Jun; 64:688-694
Alexander TH;Weisman MH;Derebery JM;Espeland MA;Gantz BJ;Gulya AJ;Hammerschlag PE;Hannley M;Hughes GB;Moscicki R;Nelson RA;Niparko JK;Rauch SD;Telian SA;Brookhouser PE;Harris JP;  Safety of high-dose corticosteroids for the treatment of autoimmune inner ear disease; Otol Neurotol ; 2009 Jun; 30:443-448
Resnick SM;Espeland MA;Jaramillo SA;Hirsch C;Stefanick ML;Murray AM;Ockene J;Davatzikos C;  Postmenopausal hormone therapy and regional brain volumes: the WHIMS-MRI Study; Neurology; 2009 Jan 13; 72:135-142
Phelan S;Kanaya AM;Subak LL;Hogan PE;Espeland MA;Wing RR;Burgio KL;DiLillo V;Gorin AA;West DS;Brown JS;  Prevalence and risk factors for urinary incontinence in overweight and obese diabetic women: action for health in diabetes (look ahead) study; Diabetes Care; 2009 Aug; 32:1391-1397
Bhasin S;Espeland MA;Evans WJ;Ferrucci L;Fried LP;Gill TM;Pahor M;Studenski S;Guralnik J;Nayfield S;Romashkin S;Perlstein R;Burke L;Parks M;  Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators; J Gerontol A Biol Sci Med Sci ; 2009 Apr; 64:487-491
Rejeski WJ;Marsh AP;Chmelo E;Prescott AJ;Dobrosielski M;Walkup MP;Espeland M;Miller ME;Kritchevsky S;  The Lifestyle Interventions and Independence for Elders Pilot (LIFE-P): 2-year follow-up; J Gerontol A Biol Sci Med Sci ; 2009 Apr; 64:462-467
Johnson KC;Margolis KL;Espeland MA;Colenda CC;Fillit H;Manson JE;Masaki KH;Mouton CP;Prineas R;Robinson JG;Wassertheil-Smoller S;  A Prospective Study of the Effect of Hypertension and Baseline Blood Pressure on Cognitive Decline and Dementia in Postmenopausal Women: The Women's Health Initiative Memory Study; J Am Geriatr Soc; 2008 Jul 15; 56:1449-1458
Rejeski WJ;King AC;Katula JA;Kritchevsky S;Miller ME;Walkup MP;Glynn NW;Pahor M;Rushing S;  Physical activity in prefrail older adults: confidence and satisfaction related to physical function; J Gerontol B Psychol Sci Soc Sci; 2008 Jan; 63:19-26
Cann JA;Register TC;Adams MR;St Clair RW;Espeland MA;Williams JK;  Timing of estrogen replacement influences atherosclerosis progression and plaque leukocyte populations in ApoE-/- mice; Atherosclerosis; 2008 Feb 21;

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